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Imidazole 288-32-4
Imidazole group denotes a heterocyclic organic compound whose molecule contains a five-membered hetero-aromatic ring of two non-adjacent nitrogen atoms, that a carbon atom is placed between two nitrogen atoms. Imidazole is the universally used trivial name for 1,3-azole. Earlier given names were glyoxaline and iminazole. The importance of this aromatic ring system is reflected by its presence in naturally occurring histidine, histamine and the purines, and in several classes of pharmaceuticals. Imidazole can act as a base and as a weak acid. It exists in two tautomeric forms with the hydrogen atom taking position between the two nitrogen atoms.

Product Parameters

Chemical Name:Imidazole

CAS No.:288-32-4

Product Categories:Chemical Pesticides

Molecular Formula:C3H4N2

Formula Weight:68.08

Appearance:White Crystalline

Packaging Method:25kg/Fiber Drum

Type Of Transportation:By Air/By Sea/By Train/By Express

Sample:Available

Chemical Properties Of Imidazole 288-32-4

Melting point88-91 °C(lit.)
Boiling point256 °C(lit.)
density1.01 g/mL at 20 °C
vapor pressure<1 mm Hg ( 20 °C)
refractive index1.4801
Fp293 °F
storage temp.Store below +30°C.
solubilityH2O: 0.1 M at 20 °C, clear, colorless
pka6.953(at 25℃)
formcrystalline
colorwhite
Specific Gravity1.03
OdorAmine like
PH Range9.5 – 11
PH9.5-11.0 (25℃, 50mg/mL in H2O)
Water Solubility633 g/L (20 ºC)
SensitiveHygroscopic
λmaxλ: 260 nm Amax: 0.10 λ: 280 nm Amax: 0.10
Merck14,4912
BRN103853
Dielectric constant23.0(Ambient)
Stability:Stable. Incompatible with acids, strong oxidizing agents. Protect from moisture.
InChIKeyRAXXELZNTBOGNW-UHFFFAOYSA-N
LogP-0.02 at 25℃
CAS DataBase Reference288-32-4(CAS DataBase Reference)
NIST Chemistry Reference1H-Imidazole(288-32-4)
EPA Substance Registry SystemImidazole (288-32-4)

Safety Information Of Imidazole 288-32-4

Hazard CodesC,Xi,T
Risk Statements36/38-63-34-22-20/21/22-61
Safety Statements26-36/37/39-45-22-36-27-53
RIDADRUN 2923 8/PG 3
WGK Germany1
RTECSNI3325000
Autoignition Temperature480 °C
TSCAYes
HazardClass8
PackingGroupIII
HS Code29332990
Hazardous Substances Data288-32-4(Hazardous Substances Data)
ToxicityLD50 in mice (mg/kg): 610 i.p.; 1880 orally (Nishie)

Product Application Of Imidazole 288-32-4

Imidazole is used as a buffer in the range of pH 6.2-7.8. It is also an histamine antagonist. It acts as a chelator and forms complexes with various divalent cations. It is used as a corrosion inhibitor on certain transition metals such as copper. Its derivatives, like polybenzimidazole (PBI), act as fire retardants. It finds application in photography and electronics. Imidazole salts are used as ionic liquids and precursors to stable carbenes. Imidazole derivatives like ketoconazole, miconazole and clotrimazole are involved in the treatment of various systemic fungal infections. It is a part of the theophylline molecule, present in tea leaves and coffee beans, which stimulates the central nervous system.


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